Exploratory study demonstrates enhanced imaging of vascular and biliary anatomy in living donors.
Motivation: Liver donor evaluation requires high-quality imaging to evaluate vascular and biliary anatomy, and is traditionally performed using multiple modalities,which can be challenging for both patients and physicians. Goal(s): Explore the use of dual-contrast agent MRCP to better define donor anatomy as an alternative to the combined use of CTA and single-contrast MRCP. Approach: Dual-contrast MRCP was performed using gadobenate dimeglumine for dynamic arterial-phase imaging, followed by gadoxetate disodium for biliary imaging. Results: From November 2022 to October 2024, 52 potential donors were scanned, 7 underwent partial hepatectomy, only one of which required additional CTA to verify complex arterial anatomy. None had postoperative complications. Impact: Dual-contrast agent MRI and MRCP can be used as a one-stop shop for high-quality arterial and biliary imaging of living liver donors, reducing radiation exposure, cost and time constraints.
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Chahine et al. (2025) studied this question.
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