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This is a Experimental Study study.

Towards genuine 3D DWI with physiological motion compensation: the feasibility on 3T with high performance gradients

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The 0.8 mm isotropic 3D DTI demonstrates higher SNR than a 2D SMS across identical scan times.
Feasibility was confirmed for both 0.8 mm and 0.6 mm isotropic resolution scans using advanced gradients.
High performance gradients alleviate TE lengthening in gradient moment nulling implementation.
Direct 3D DTI surpasses 2D SMS scans at ultra-high spatial resolution, potentially altering clinical protocols.

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Investigation reveals high resolution 3D DTI improves SNR in scans, suggesting enhanced imaging quality with advanced gradients.

Wang et al. (2025) studied this question.

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