Supplementary Figure S5 from Response to Antiangiogenic Therapy Is Associated with AIMP Protein Family Expression in Glioblastoma and Lower-Grade Gliomas

Humaira Noor; Yuanning Zheng; Haruka Itakura; Olivier Gevaert

doi:10.1158/2767-9764.30134681

September 16, 2025Open Access

Supplementary Figure S5 from Response to Antiangiogenic Therapy Is Associated with AIMP Protein Family Expression in Glioblastoma and Lower-Grade Gliomas

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Key Points

A higher expression of AIMP proteins correlates with different responses to antiangiogenic therapy in glioblastoma.
Spatial distribution analysis shows distinct patterns of AIMP1 and AIMP3 across tumor tissues in glioblastoma samples.
The study focuses on understanding AIMP protein expression in lower-grade gliomas compared to glioblastoma.
Therapeutic strategies may benefit from targeting AIMP protein family expression in glioblastoma and lower-grade gliomas.

Implication

Analysis reveals spatial distribution of AIMP1 and AIMP3 in glioblastoma and lower-grade gliomas, highlighting their potential role in therapy response.

Abstract

Spatial distribution of AIMP1 and AIMP3 expression across tumor tissues in two representative GBM slides

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Cite This Study

Noor et al. (2025) studied this question.

synapsesocial.com/papers/68d45e5831b076d99fa5e8cf https://doi.org/10.1158/2767-9764.30134681

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Supplementary Figure S5 from Response to Antiangiogenic Therapy Is Associated with AIMP Protein Family Expression in Glioblastoma and Lower-Grade Gliomas

Key Points

Implication

Abstract

Discussion

Cite This Study

Supplementary Figure S5 from Response to Antiangiogenic Therapy Is Associated with AIMP Protein Family Expression in Glioblastoma and Lower-Grade Gliomas

Key Points

Implication

Abstract

Discussion

Cite This Study

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