This article discusses advancements using hot melt extrusion and 3D printing for customizable drug dosage forms, indicating improved patient compliance.
Recent advancements in pharmaceutical manufacturing are paving the way for highly personalized and on-demand therapies. This article discusses a novel approach that integrates Hot Melt Extrusion (HME) with 3D printing to produce drug dosage forms with customizable immediate- and modified-release profiles. By transforming APIs and polymers into drug-loaded filaments and then precisely printing them into dosage forms, this method addresses longstanding challenges, such as limited control over drug distribution and suboptimal solubility, while enhancing patient compliance. The innovative design not only promises tailored dosing regimens but also provides significant advantages in production efficiency and regulatory compliance.
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Kumar et al. (2025) studied this question.
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