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This is a Experimental Study study.

Formulation and Evaluation of Pulsatile-Release Multiple-Unit Pellets of Meloxicam

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Formulation F4 optimized pulsatile drug release in response to coating materials, suggesting potential for enhanced therapeutic effects.

Formulation F4 showed a significant drug release of 96.8% by 8 hours, indicating effective pulsatile delivery.
All batches demonstrated strong mechanical stability with friability under 1%, ensuring durability of the pellets.
Drug content analysis revealed formulations maintaining high levels, notably F4 at 99.4 ± 1.2%, ensuring therapeutic efficacy.
The stability study indicated minimal changes in drug release and content over three months under accelerated conditions.

Lahane et al. (2025) studied this question.

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