Current evidence of sinonasal carcinoma for clinical practitioners. Part 2

Sinonasal carcinoma (SNC) is the most common malignant tumor of the nasal cavity and paranasal sinuses. Sinonasal carcinoma includes seven main histopatological subtypes and three most common have been presented in Part 1 of this manuscript. In the following, Part 2 of the manuscript the remaining four even more rare subtypes like olfactory neuroblastoma (ONB), sinonasal neuroendocrine carcinoma (snNEC), nuclear protein in testis carcinoma (NUT) and sinonasal undifferentiated carcinoma (snUC) are presented and discussed as to the epidemiology, etiology, clinical course, methods of treatment and outcome. It should be emphasized however that patients suspected of having a rare cancer should be directed to oncology centers with proven expertise in managing these uncommon malignancies.