September 17, 2025Reproduction and FertilityOpen Access

Chronic endometritis diagnosis and fertility outcomes: An old unresolved question

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Retrospective study evaluates chronic endometritis diagnosis in infertile women, highlighting immunohistochemical methods and antibiotic effects.

Pregnancy rate was significantly higher in treated patients (53%) compared to untreated patients (20%), suggesting antibiotic therapy may improve outcomes.
Hysteroscopy showed low sensitivity (22%) but high specificity (100%) for diagnosing chronic endometritis when compared to immunohistochemistry.
Assessment of chronic endometritis relied heavily on the presence of plasma cells via immunostaining, with moderate consistency in readings.
The study involved 51 infertile women who underwent hysteroscopy and endometrial biopsy to evaluate chronic endometritis and fertility effects.

Ilic et al. (2025) studied this question.

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Retrospective study evaluates chronic endometritis diagnosis in infertile women, highlighting immunohistochemical methods and antibiotic effects.