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September 17, 2025

Newer Therapies for Osteoporosis: A Systematic Review.

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Authors

PDParthajit DasMGMohit GoyalDRDebaditya Roy

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Overview

Systematic review evaluates newer therapies for osteoporosis, showing significant bone density improvements and fracture risk reductions.

Key Points

  • Newer therapies for osteoporosis showed significant bone mineral density gain and fracture risk reduction.
  • Eighteen randomized controlled trials involving over 22,000 postmenopausal women and men were assessed for outcomes.
  • Anabolic agents like abaloparatide and romosozumab demonstrated superior efficacy compared to traditional treatments.
  • A sequential therapeutic strategy using anabolic agents followed by antiresorptive agents proved more effective.

Cite This Study

Das et al. (2025) studied this question.

synapsesocial.com/papers/68d4605931b076d99fa5fe4ehttps://doi.org/10.59556/japi.73.1084
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Effectiveness of anabolic and anti-resorptive agents for preventing postmenopausal osteoporosis fractures: a systematic review and network meta-analysis2025 · 14 citations
  2. 2Combination and sequential therapy for postmenopausal osteoporosis: recent advances and clinical practice2026
  3. 3Recent Advances in Osteoporosis Therapeutics2025
  4. 4Comparison of the Clinical Efficacy of Anabolic Agents and Bisphosphonates in the Patients With Osteoporotic Vertebral Fracture: Systematic Review and Meta-analysis of Randomized Controlled Trials2024 · 15 citations
  5. 5Comparative efficacy and safety of antiresorptive and anabolic therapies for male osteoporosis: an updated Bayesian network meta-analysis2026