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September 17, 2025CureusOpen Access

Efficacy of Topical Corticosteroid Therapy in Chronic Rhinosinusitis Post-endoscopic Sinus Surgery: A Narrative Synthesis of Randomized Controlled Trials

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Authors

SASuzan AlharbiQassim UniversityEAElaf M Al-JuaidSASaad AlghamdiUmm al-Qura University

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Implication

Narrative synthesis shows topical corticosteroids improve mucosal recovery in CRS, highlighting efficacy and safety.

Key Points

  • Topical corticosteroid therapy significantly enhances mucosal recovery in patients post-endoscopic sinus surgery.
  • Analysis of six randomized controlled trials involving 530 participants revealed reduced rates of adhesion and polyp recurrence.
  • Following the PRISMA framework, data extraction and quality appraisal were performed independently by reviewers to ensure reliability.
  • Findings emphasize the benefits of localized corticosteroids in reducing complications while suggesting the need for further studies.

Cite This Study

Alharbi et al. (2025) studied this question.

synapsesocial.com/papers/68d461b631b076d99fa6063bhttps://doi.org/10.7759/cureus.92274
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Also Consider

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  1. 1Cross-Regional Comparison of Type 2 Inflammatory Markers in Chronic Rhinosinusitis With Nasal Polyposis: Insights From the Gulf Region and Canada.2025
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  4. 4Efficacy of Steroid-Impregnated Spacers After Endoscopic Sinus Surgery in Chronic Rhinosinusitis: A Systematic Review and Meta-Analysis2023 · 28 citations
  5. 5The Role of Corticosteroid Nasal Irrigations in the Management of Chronic Rhinosinusitis: A State-of-the-Art Systematic Review2023 · 16 citations