Crossed Cerebellar Diaschisis Secondary to Acute Drug-Induced Liver Failure: A Case Report

Abstract Crossed cerebellar diaschisis (CCD) is a phenomenon in which a unilateral cerebral lesion provokes reduced neuronal metabolism and hypoperfusion in the contralateral cerebellar hemisphere[1]. It is most often observed in acute ischemic stroke[2] and status epilepticus[3] among other central nervous system emergencies. We present a rare case of CCD secondary to acute druginduced liver failure following acetaminophen overdose, complicated by profound hypoglycemic encephalopathy. This report broadens the etiologic spectrum of CCD and underscores the relevance of systemic metabolic disturbances in its pathophysiology.