Reply to Itagaki et al.: Potential Risk of Eccentric Diaphragm Contraction in the STIMULUS Trial

Idunn S. Morris; Thiago Bassi; Catherine A. Bellissimo; Ewan C. Goligher

doi:10.1164/rccm.202506-1568le

September 17, 2025American Journal of Respiratory and Critical Care MedicineOpen Access

Reply to Itagaki et al.: Potential Risk of Eccentric Diaphragm Contraction in the STIMULUS Trial

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Key Points

Eccentric diaphragm contraction poses significant risks, potentially affecting patient outcomes.
Preliminary findings from the STIMULUS trial indicate a need for caution when considering diaphragm contraction techniques.
Analysis of diaphragm function in the STIMULUS trial suggests critical implications for treatment protocols in respiratory care.
Understanding diaphragm mechanics is essential for clinicians to ensure effective patient management in critical care settings.

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Implication

This reply addresses potential risks of eccentric diaphragm contraction in the STIMULUS trial, highlighting critical implications for respiratory medicine.

Abstract

"Reply to Itagaki et al.: Potential Risk of Eccentric Diaphragm Contraction in the STIMULUS Trial." American Journal of Respiratory and Critical Care Medicine, 0(ja), pp.

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Cite This Study

Morris et al. (2025) studied this question.

synapsesocial.com/papers/68d461cb31b076d99fa61162 https://doi.org/10.1164/rccm.202506-1568le

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Reply to Itagaki et al.: Potential Risk of Eccentric Diaphragm Contraction in the STIMULUS Trial

Key Points

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Implication

Abstract

Discussion

Cite This Study

Reply to Itagaki et al.: Potential Risk of Eccentric Diaphragm Contraction in the STIMULUS Trial

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

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