A clinical case of successful treatment of surgical site infection in a kidney and pancreas recipient

Background. Surgical site infections (SSIs) following solid organ transplantation pose grave risks, including the potential loss of the transplanted organ and mortality of the recipient. The management of these infections is highly intricate and necessitates ongoing research and the refinement of treatment protocols to enhance outcomes. The objective of this study is to illustrate a successful treatment approach for retroperitoneal infection in the surgical area following combined kidney and pancreas transplantation, with a particular focus on the region where the pancreas graft is located. Material and methods. A 31-year-old female recipient of a kidney and pancreas transplant was diagnosed with type 1 diabetes mellitus, complicated by diabetic nephropathy, which had progressed to a terminal stage of chronic kidney disease. The clinical case was described using data from the recipient's medical history, observation card, and organ passport, along with the results of general clinical and instrumental investigations. Results. The clinical picture of the course of bacterial infection of the retroperitoneal space in the area of pancreas graft location and its successful treatment in a recipient after simultaneous pancreas and kidney transplantation is presented. Due to the choice of optimal treatment tactics, it was possible not only to avoid the development of sepsis, but also to preserve the function of both grafts. Conclusion. The development of SSIs in the form of retroperitoneal infection in a recipient without primary infection of the pancreas graft, in the context of adequate surgical intervention, in conjunction with etiotropic antimicrobial therapy and a reduction in immunosuppression, is a condition that can be effectively treated, resulting in a positive outcome for the recipient.