Ensuring data privacy and security in sensitive domains such as healthcare remains a critical challenge. Homomorphic Encryption (HE) offers a promising approach by enabling computations directly on encrypted data, but the diversity of available schemes requires careful evaluation before practical adoption. This work conducts a comparative study of six representative HE schemes: BGV, TFHE, Paillier, RSA without padding, BFV, and CKKS. It is adopted a five-step strategy, encompassing preprocessing, cryptographic setup, encryption, homomorphic execution, and decryption, applied to a healthcare dataset. Overall, the comparative analysis underscores that no single scheme is universally optimal. The choice of an HE scheme must be guided by the nature of the required operations, acceptable precision levels, and computational constraints of the target healthcare scenario.
Jorge et al. (Wed,) studied this question.