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September 18, 2025Cancer Epidemiology Biomarkers & Prevention

Abstract B153: Age-related disparities in acute lymphoblastic leukemia: Hispanic patients present two decades earlier with distinct clinical features

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Authors

MSMatthew SlaughtVirginia Mason Medical CenterGGGeorge GrantUniversity of AberdeenEBElizabeth BrémUC Irvine Health

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Overview

Retrospective cohort analysis highlights earlier age at diagnosis and distinct clinical features in Hispanic patients with acute lymphoblastic leukemia.

Key Points

  • Hispanic patients diagnosed with acute lymphoblastic leukemia at a mean age of 41.2 years, significantly earlier than non-Hispanic patients.
  • The age difference of nearly 20 years underscores stark health disparities, necessitating deeper investigation into underlying causes.
  • Statistical comparisons reveal comparable complete remission rates and notable differences in measurable residual disease positivity among ethnic groups.
  • These findings stress the importance of addressing ethnicity-specific risk factors to improve outcomes for Hispanic patients with acute lymphoblastic leukemia.

Cite This Study

Slaught et al. (2025) studied this question.

synapsesocial.com/papers/68d463f131b076d99fa637cdhttps://doi.org/10.1158/1538-7755.disp25-b153
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Abstract A032: Disparities in molecular subtypes of acute lymphoblastic leukemia incidence by age, race/ethnicity, and sex in the United States2024
  2. 2Abstract 2846: Investigation of mechanisms that result in health disparity for Hispanic/Latino patients with B acute lymphoblastic leukemia2024
  3. 3Abstract A091: Clinical and demographic differences between children and young adult US-born and non-US-born Latinos diagnosed with classical Hodgkin Lymphoma in the MESH Study Cohort2025
  4. 4Abstract C087: Distinct gene expression and DNA methylation pattern associated with poor outcome of B-cell acute lymphoblastic leukemia in Hispanic/Latino children2024
  5. 5Racial disparities in pediatric patients with acute lymphoblastic leukemia: An National Cancer Database analysis2024 · 1 citations