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September 18, 2025Cancer Epidemiology Biomarkers & Prevention

Abstract B152: County-level particulate matter 2.5 exposure associated with higher rates of pediatric leukemia in Southeast Texas

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Authors

AOAndreas OttoJSJeremy M. SchrawTHThanh T. Hoang

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Overview

Observational analysis found higher leukemia rates associated with PM2.5 in Hispanic children, suggesting significant health disparities by race/ethnicity.

Key Points

  • Higher PM2.5 exposure correlates with increased leukemia incidence in pediatric patients, particularly among Hispanic children.
  • Rate ratios for total leukemia were 1.28 and for ALL were 1.35 in high PM counties compared to low PM counties.
  • Linear regression showed a significant increase in ALL incidence with increased PM2.5 exposure among Hispanic and some other racial/ethnic groups.
  • The study underlines the need for targeted public health interventions to mitigate environmental health disparities.

Cite This Study

Otto et al. (2025) studied this question.

synapsesocial.com/papers/68d463f131b076d99fa637e5https://doi.org/10.1158/1538-7755.disp25-b152
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Particulate Matter Exposure during Pregnancy and Childhood Leukemia Incidence2024 · 3 citations
  2. 2A18-02 Component-specific Pm2.5 Associations With Pediatric Asthma Emergency Department Visits in Texas Cities: Role of Neighborhood Context2026
  3. 3Abstract B011: Associations between county-level air pollutants and early-onset breast cancer incidence rates in the U.S2025
  4. 4Abstract A048: Association between ambient particulate matter and colorectal cancer incidence: The Multiethnic Cohort Study2024
  5. 5Abstract 3456: The role of particulate matter exposure in racial differences in colorectal cancer mortality in metropolitan Detroit2024