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September 19, 2025Prague Medical ReportOpen Access

Navigating Diagnostic Complexity in Hailey-Hailey Disease: A Case Report with Clinical-histopathological Correlation

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Authors

PGParth GoswamiGSGyanendra SinghVPVarniraj Patel

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Overview

This case report demonstrates clinical-histopathological correlation in a patient with Hailey-Hailey disease, highlighting key diagnostic features.

Key Points

  • A patient with a ten-year history of Hailey-Hailey disease exhibited characteristic symptoms and histopathological findings.
  • Histopathological analysis revealed significant epidermal hyperkeratosis and acantholysis, confirming the diagnosis of HHD.
  • The case underscores the necessity of differential diagnosis, eliminating conditions like Darier disease and pemphigus vegetans.
  • Timely diagnosis and individualized management can enhance outcomes for patients affected by Hailey-Hailey disease.

Cite This Study

Goswami et al. (2025) studied this question.

synapsesocial.com/papers/68d464ea31b076d99fa63ff6https://doi.org/10.14712/23362936.2025.27
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