Randomized controlled trial shows PRP enhances bone regeneration and implant stability in patients.
Osseointegration and peri-implant bone regeneration are critical determinants of long-term dental implant success, yet achieving optimal outcomes remains challenging. Platelet-Rich Plasma (PRP), enriched with autologous growth factors, has been proposed as an adjunctive biomaterial to enhance bone healing. In this randomized controlled clinical trial, 30 patients requiring single implants were allocated to PRP-coated (Group A) and non-PRP (Group B) groups. Group A demonstrated significantly higher implant stability quotient (ISQ) values and peri-implant bone density compared to controls at 3 months. Thus, we show that PRP application may effectively improve implant stability and peri-implant bone regeneration.
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Jalaluddin et al. (2025) studied this question.
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