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September 19, 2025Siberian Journal of Clinical and Experimental MedicineOpen Access

Antibacterial and antimycotic activity of benzophenazine derivatives: an in vitro study

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Authors

VNV. V. NadtochiyAAAqeel M.K. AltobeePAP. G. Amineva

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Overview

In vitro analysis shows promising antibacterial and antifungal activity of benzophenazine derivatives, indicating potential for new antimicrobial agents.

Key Points

  • All tested benzophenazine derivatives showed antibacterial activity against Streptococcus agalactiae and Burkholderia cenocepacia.
  • Unsubstituted benzophenazine-5-ol (VN-13) demonstrated activity against other tested strains, highlighting its potential as an antimicrobial agent.
  • Pseudomonas aeruginosa and Escherichia coli ATCC 25922 were resistant to all studied benzophenazine compounds.
  • Benzophenazine derivatives suggest efficacy against polyresistant strains, with continued research warranted for their safety and effectiveness.

Cite This Study

Nadtochiy et al. (2025) studied this question.

synapsesocial.com/papers/68d466a831b076d99fa650d9https://doi.org/10.29001/2073-8552-2025-2725
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