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September 19, 2025Acta Cirúrgica BrasileiraOpen Access

Investigation of the protective efficacy of Caesalpinia sappan and spirulina against ethanol-induced experimental rat gastritis model

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Authors

İOİdris OruçDiyarbakır Gazi Yaşargil Eğitim ve Araştırma HastanesiZKZelal KarakoçDicle UniversityFAFiliz AkdumanState Hospital

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Implication

Experimental research shows caesalpinia sappan and spirulina reduce inflammation and oxidative stress in gastritis, indicating potential therapeutic benefits.

Key Points

  • Caesalpinia sappan and spirulina significantly reduced inflammation in a rat model of gastritis.
  • The treatment increased CD8 and CD68 expression while decreasing MHC I and II levels.
  • Rats treated with C. sappan and spirulina showed improved oxidative stress markers, including decreased malondialdehyde levels.
  • This research highlights the potential of natural compounds in protecting gastric tissues from damage caused by ethanol.

Cite This Study

Oruç et al. (2025) studied this question.

synapsesocial.com/papers/68d466c431b076d99fa65ed4https://doi.org/10.1590/acb406725
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Also Consider

Synapse has enriched one closely related paper. Consider it for comparative context:

  1. 1Antioxidant activity and potential of Caesalpinia sappan aqueous extract on synthesis of silver nanoparticles2018 · 32 citations