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September 20, 2025Journal of Functional BiomaterialsOpen Access

Engineering Metal-Organic Frameworks for Enhanced Antimicrobial Efficacy: Synthesis Methodologies, Mechanistic Perspectives, and Versatile Applications

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Authors

ZZZaixiang ZhengYangzhou UniversityJCJunnan CuiYangzhou UniversitySWShutong WuYangzhou University

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Overview

This review highlights antibacterial mechanisms of metal-organic frameworks, emphasizing synthesis and applications.

Key Points

  • Metal-organic frameworks show promise against antibiotic resistance, demonstrating unique antibacterial mechanisms.
  • Approximately 4.95 million deaths were linked to antimicrobial resistance in 2019, indicating an urgent health crisis.
  • The review focuses on structure–function relationships of metal-organic frameworks to outperform traditional antimicrobials.
  • Clinical translation challenges remain for metal-organic frameworks, yet they offer significant potential for antimicrobial therapy.

Cite This Study

Zheng et al. (2025) studied this question.

synapsesocial.com/papers/68d469ba31b076d99fa662bbhttps://doi.org/10.3390/jfb16090353
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