Antiretroviral Therapy and Sickle Cell Disease: Balancing Efficacy and Toxicity

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Assessment of antiretroviral therapy's effects on organ damage in sickle cell disease, suggesting a nuanced approach.

Antiretroviral therapy provides benefits for managing HIV in patients with sickle cell disease, but monitoring is crucial.
As sickle cell disease progresses, patients frequently experience hemolysis and acute pain, complicating their treatment.
Management strategies for sickle cell disease must consider both efficacy and potential toxicity of therapies involved.
Continuous monitoring of organ function is essential due to the risk of damage from both sickle cell disease and HIV.

Emmanuel Ifeanyi Obeagu (2025) studied this question.

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