(De)coding SABRE of [1-¹³C]Pyruvate

Q: What type of study is this?

This is a Experimental Study study.

Salvatore Mamone; Federico Floreani; Ahmed Faramawy; Claudia Graiff; Lorenzo Franco; Marco Ruzzi; Cristina Tubaro; Gabriele Stevanato

doi:10.1039/d5cp01773d

January 1, 2025Physical Chemistry Chemical PhysicsOpen Access

(De)coding SABRE of [1-¹³C]Pyruvate

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Key Points

Efficient signal amplification was achieved in hyperpolarized pyruvate, enhancing imaging capabilities.
Results indicated that the new SABRE approach improved the ¹³C signal compared to previous methods.
The study employed a systematic methodology, integrating advanced imaging techniques and analysis.
These findings support the potential of hyperpolarized pyruvate for more effective biomedical applications.

Implication

Comprehensive study reveals improved signal amplification in hyperpolarized pyruvate, indicating better biomedical imaging.

Abstract

Hyperpolarized pyruvate is a key molecular probe for biomedical imaging, but achieving efficient ¹³C Signal Amplification By Reversible Exchange (SABRE) enhancement remains elusive. Here, we report a comprehensive study integrating...

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Cite This Study

Mamone et al. (2025) studied this question.

synapsesocial.com/papers/68d469c831b076d99fa6694f https://doi.org/10.1039/d5cp01773d

View Full Paper

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(De)coding SABRE of [1-¹³C]Pyruvate

Key Points

Implication

Abstract

Discussion

Cite This Study

(De)coding SABRE of [1-¹³C]Pyruvate

Key Points

Implication

Abstract

Discussion

Cite This Study

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