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September 20, 2025Current Neurovascular Research

Causal Relationship Between Hypertension And Vertigo: A Mendelian Randomization Study

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Authors

LWLinrong WuYSYiming ShenTLTian li

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Overview

Mendelian randomization reveals a positive association between hypertension and vertigo risk, suggesting vascular influences in certain vertigo types.

Key Points

  • Hypertension significantly correlates with an increased risk of total vertigo, particularly BPPV and peripheral vertigo.
  • Instrumental variables were based on 53 SNPs linked to hypertension, indicating a robust genetic basis for analysis.
  • The study utilized a two-sample MR approach to overcome observational study limitations concerning vertigo subtypes.
  • Findings suggest that hypertension may cause vestibular dysfunction, highlighting the importance of addressing vascular risk factors.

Cite This Study

Wu et al. (2025) studied this question.

synapsesocial.com/papers/68d46ab431b076d99fa679e8https://doi.org/10.2174/0115672026379859250910094729
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