This review highlights the metaplastic transformation into columnar epithelium, indicating potential malignancy risks.
Barrett’s esophagus is a pathological process where the inflammatory milieu created within the esophagus leads to progressive changes over time that can lead eventually to frank malignancy. It is a pre-malignant condition and involves a metaplastic transformation of the distal epithelium of the esophagus. There is a conversion of the normal type of squamous epithelium into the columnar type of epithelium. There are several risk factors associated with this condition and it is typically diagnosed endoscopically. This review article provides a brief overview of this condition.
No takes yet. Share an insight, caveat, or question.
Chela et al. (2025) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: