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This is a Quantitative Study study.

September 20, 2025Open Access

Geometry of disordered porous environments regulates cell migration

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Cell migration is regulated by the porous structure of the extracellular matrix, impacting tissue organization.
The study reveals that spatial heterogeneities in porosity direct cell movement towards regions of low porosity.
Using a cellular Potts model, distinct motility regimes like 'hopping' were identified during cell migration.
Understanding these dynamics may enhance insights into conditions like chronic inflammation and cancer.

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This research uncovers how porosity influences cell migration patterns in disordered environments, highlighting motility dynamics.

Würthner et al. (2025) studied this question.

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