Commentary discusses diagnostic sensitivity using formalin-fixed faecal microscopy, highlighting implications for WHO guidelines and endemic settings.
We commend the study by Larkins et al. on the diagnostic sensitivity of formalin-fixed faecal microscopy for soil-transmitted helminths, particularly their introduction of the McMaster2 method. This innovation demonstrates superior sensitivity while preserving practicality for field use. We highlight key implications for national control programs in endemic settings, especially those constrained by limited infrastructure and cold-chain logistics. This commentary expands on potential regional adaptations, cost-effectiveness and integration into the World Health Organization guidelines and operational frameworks. Further evaluation of this method's utility in diverse epidemiological and health system contexts is warranted.
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Rattanapitoon et al. (2025) studied this question.
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