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September 20, 2025

Development and Validation of a Nomogram for Predicting Specific Mortality Risk After Surgery for Locally Advanced Rectal Cancer: Studies Based on SEER Database and External Validation Cohorts.

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Authors

STShufa TanSLShuang LiuYYYunyi Yang

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Overview

Retrospective cohort analysis predicts cancer-specific mortality in rectal cancer patients, indicating a novel clinical tool.

Key Points

  • The competing risk model predicts cancer-specific mortality with high accuracy in patients with locally advanced rectal cancer.
  • AUC values reached 0.795 for 1-year predictions in the training cohort, confirming robust predictive capacity.
  • Retrospective cohort design included 7608 patients diagnosed with locally advanced rectal cancer between 2010 and 2015.
  • The model's findings suggest limited utility of log odds of positive lymph nodes alone as a predictor of mortality outcomes.

Cite This Study

Tan et al. (2025) studied this question.

synapsesocial.com/papers/68d46abb31b076d99fa67ec6https://doi.org/10.1177/10732748251378203
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Also Consider

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  5. 5A competing-risk nomogram to predict cause-specific death in elderly patients with colorectal cancer after surgery (especially for colon cancer)2020 · 25 citations