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September 20, 2025

Elucidating the Pharmacological Basis of Xianling Cifang Granules Against Breast Cancer. A Metabolomic Profiling Study.

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Authors

YWYang WangRYRui YangYSYouyang Shi

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Overview

Metabolomic profiling unveils key constituents and targets in treating breast cancer, highlighting pharmacological pathways.

Key Points

  • Icaritin, identified as a key constituent, exhibited anti-breast cancer activity by inducing apoptosis and modulating the immune environment.
  • A total of 122 prototype constituents from Xianling Cifang Granules entered circulation, impacting crucial metabolic pathways related to inflammation.
  • The integration of network pharmacology and molecular docking illustrated stable interactions between Icaritin and critical targets like ADORA1.
  • This research underscores the pharmacological potential of Xianling Cifang Granules in breast cancer therapy, warranting further validation.

Cite This Study

Wang et al. (2025) studied this question.

synapsesocial.com/papers/68d46abb31b076d99fa67f71https://doi.org/10.2147/dddt.s530516
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