This method demonstrates halophosphonium salts acting as photocatalysts and reagents for C(sp3)–H functionalization, suggesting new pathways for green organic synthesis.
Herein we report a method that uses halophosphonium salts as dual-function reagents for versatile C(sp3)–H functionalization under visible light. They serve simultaneously as photocatalysts and hydrogen atom transfer reagents, eliminating the need for exogenous metal catalysts. This strategy enables benzylic, allylic, and aliphatic C–H alkylation, hydrazination, and cyanation. The discovery significantly expands the synthetic utility of halophosphonium salts beyond their classical roles, establishing them as modular photochemical scaffolds for green organic synthesis.
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Sun et al. (2025) studied this question.
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