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September 21, 2025Environmental Toxicology

Protective Effects of Safranal Against Paraquat‐Induced Acute Lung Injury in Rat

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Authors

SBSima BeigoliAMArghavan MemarziaMMMonireh Mahjoob

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Overview

Animal study reveals that safranal improves lung function in rats exposed to paraquat, suggesting anti-inflammatory benefits.

Key Points

  • Safranal significantly improves protective effects against lung injury caused by paraquat exposure.
  • Improvements were observed in SOD and CAT levels, with p values ranging from < 0.05 to < 0.001.
  • The combination of safranal and pioglitazone showed enhanced effects compared to either treatment alone.
  • Findings suggest involvement of the PPARγ receptor in the protective mechanisms of safranal.

Cite This Study

Beigoli et al. (2025) studied this question.

synapsesocial.com/papers/68d46ac231b076d99fa681a9https://doi.org/10.1002/tox.24561
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