Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
September 21, 2025Journal of Child Psychology and PsychiatryOpen Access

Mapping phenotypic and genetic relationships among irritability, depression and ADHD in adolescence using network analysis

View Full Paper
Ask AI
Bookmark
Share

Authors

ASAmy ShakeshaftCardiff UniversityLFLuís C. FarhatUniversidade de São PauloCDCharlotte DennisonCardiff University

Discussion

Loading...

Member takes

Implication

Network analysis reveals significant connections between irritability, ADHD, and depression, suggesting new treatment directions.

Key Points

  • Irritability shows strong associations with headstrong/hurtful ODD items, ADHD, and depression.
  • Network analyses in ALSPAC revealed that irritability connects ADHD and depression, and PGS highlighted this link.
  • Secondary analysis using alternative questionnaires confirmed previous findings of strong relationships between these conditions.
  • Findings support the ICD-11 view of irritability as a symptom that warrants attention in youth with ADHD.

Cite This Study

Shakeshaft et al. (2025) studied this question.

synapsesocial.com/papers/68d46cb831b076d99fa684a6https://doi.org/10.1111/jcpp.70040
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Which estimation method to choose in network psychometrics? Deriving guidelines for applied researchers.2021 · 377 citations
  2. 2R: A Language and Environment for Statistical Computing2000 · 363,590 citations
  3. 3qgraph : Network Visualizations of Relationships in Psychometric Data2012 · 5,050 citations
  4. 4Childhood neurodevelopmental difficulties and risk of adolescent depression: the role of irritability2019 · 71 citations
  5. 5Irritability in Youths: A Critical Integrative Review2024 · 127 citations