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September 21, 2025Open Access

Transcranial Alternating Current Stimulation can disrupt or reestablish neural entrainment in a primate model of Parkinson's disease

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Authors

HTHarry TranUniversity of Minnesota BMBiswaranjan MohantyUniversity of Minnesota NHNoah HjelleUniversity of Minnesota

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Implication

Observational analysis uncovered how tACS modifies neural firing patterns in primates with Parkinson's, suggesting potential therapeutic implications.

Key Points

Weak electric fields disrupt beta-band spike timing patterns in a primate model, indicating a shift in neural activity.
High electric fields can reestablish neural entrainment with altered phase preferences, highlighting a complex interaction.
Frequency-matched stimulation enhances neural entrainment, suggesting important considerations for therapeutic applications.
These findings imply significant potential for tACS in modulating pathological oscillations associated with Parkinson's disease.

Cite This Study

Tran et al. (2025) studied this question.

synapsesocial.com/papers/68d46cb831b076d99fa6880f https://doi.org/10.1101/2025.09.17.676896

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Implication

Observational analysis uncovered how tACS modifies neural firing patterns in primates with Parkinson's, suggesting potential therapeutic implications.

Transcranial Alternating Current Stimulation can disrupt or reestablish neural entrainment in a primate model of Parkinson's disease

Discussion

Member takes

Implication

Key Points

Cite This Study

Transcranial Alternating Current Stimulation can disrupt or reestablish neural entrainment in a primate model of Parkinson's disease

Discussion

Member takes

Implication

Key Points

Cite This Study

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