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September 17, 2025Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition

Prediction of High and Low Expression of Tumor-Infiltrating Lymphocytes in Breast Cancer Using MRI Features Combined with Molecular Subtypes

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Authors

JZJiejie ZhouYZYang ZhangYLYan-Lin Liu

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Overview

Analysis differentiates high from low tumor-infiltrating lymphocytes in breast cancer, suggesting MRI features may enhance outcomes.

Key Points

  • The classification model based on MRI features achieved AUC values of 0.81 in training and 0.75 in testing datasets.
  • Combining MRI and clinical parameters improved prediction accuracy, with a nomogram achieving AUC of 0.82 and 0.79.
  • The SVM machine learning model outperformed others with AUC scores of 0.86 and 0.80, indicating better predictive capabilities.
  • Different molecular subtypes of breast cancer showed distinct levels of tumor-infiltrating lymphocytes, which can impact prognosis.

Cite This Study

Zhou et al. (2025) studied this question.

synapsesocial.com/papers/68d46ccf31b076d99fa690f4https://doi.org/10.58530/2025/1306
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Tumor-Infiltrating Lymphocytes (TILs) in Breast Cancer: Prognostic and Predictive Significance across Molecular Subtypes2024 · 68 citations
  2. 2AI-assisted image analysis of tumor-infiltrating lymphocytes as a prognostic marker in chemotherapy-naïve luminal breast cancer2026
  3. 3Deep learning-based and BI-RADS guided radiomics model for automatic tumor-infiltrating lymphocytes evaluation in breast cancer2024 · 1 citations
  4. 4Deep learning-based quantitative assessment of tumor-infiltrating lymphocytes from hematoxylin and eosin-stained slides in triple-negative breast cancer: A prognostic study.2024 · 4 citations
  5. 5Tumor-infiltrating lymphocytes evaluation using quantitative DCE-MRI-based habitat imaging in breast cancer patients: a preliminary study2025