This work demonstrates thiazole-based palladium precatalysts improving C-C cross-couplings in water, indicating green chemistry benefits.
Abstract The present work describes a facil access to novel nano-sized thiazole-based palladium(II) complexes from easily accessible starting precursors and elucidation of their structures by spectroscopic tools as well as physical characteristics. The efficiency of the synthesized complexes and their use as precatalysts for Suzuki Miyaura cross coupling reaction was investigated. Thiazole-based palladium(II) precatalysts could catalyze the C-C cross coupling reaction efficiently using water as a solvent under green mild reaction conditions.
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Afaf Y. Khormi (2025) studied this question.
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