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September 20, 2025JDDG Journal der Deutschen Dermatologischen Gesellschaft

Bacterial skin colonization and systemic antibiotic treatment in patients with cutaneous T‐cell lymphoma

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Authors

HWHuizhong WangSLShanshan LiYWYujie Wen

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Overview

Retrospective study finds no correlation between bacterial colonization and outcomes in CTCL patients, emphasizing ulcerated lesions as risk factors.

Key Points

  • Bacterial skin colonization was found in 85 patients, with staphylococcus aureus detected in 60.2% of cases.
  • Ulcerated lesions significantly increased the likelihood of positive bacterial and staphylococcus aureus skin cultures in analysis.
  • Retrospective analysis involving 113 cutaneous T-cell lymphoma patients tested skin swabs at Peking University First Hospital.
  • This study suggests antibiotic intervention does not correlate with overall survival in patients with cutaneous T-cell lymphoma.

Cite This Study

Wang et al. (2025) studied this question.

synapsesocial.com/papers/68d46fc631b076d99fa69ba7https://doi.org/10.1111/ddg.15865
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Also Consider

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  1. 1Prevalence and treatment of Staphylococcus aureus colonization in patients with mycosis fungoides and Sézary syndrome2008 · 192 citations
  2. 2Skin Barrier Dysfunction and Low Antimicrobial Peptide Expression in Cutaneous T-cell Lymphoma2014 · 62 citations
  3. 3WHO-EORTC classification for cutaneous lymphomas2005 · 3,821 citations
  4. 4Endolysin Inhibits Skin Colonization by Patient-Derived Staphylococcus Aureus and Malignant T-Cell Activation in Cutaneous T-Cell Lymphoma2023 · 36 citations