Case study explores drug treatment outcomes in a child with overlap syndrome, highlighting diagnostic challenges.
Background. The combination of systemic scleroderma and systemic lupus erythematosus is described sufficiently detailed in the literature. However, overlap of localized forms of scleroderma and discoid lupus erythematosus in children is described only in single clinical observations. Case description. Rare case study of overlap syndrome is presented, the results of drug treatment are demonstrated, differential diagnosis issues and disease pathogenetic features are highlighted. Conclusion. Diagnosis of overlap syndromes presents significant difficulties. Its untimely verification leads to ineffective management. As a result, persistent functional and cosmetic skin defects develop, leading to negative impact on patients' quality of life.
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Murashkin et al. (2025) studied this question.
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