Promotion of infected wound healing by black phosphorus-strontium via photothermal therapy

Bacterial infection, as one of the most common inflammatory complications of skin wounds, presents a critical challenge in clinical treatment: how to effectively control infection while preventing the emergence of drug-resistant strains. In this study, black phosphorus (BP) nanosheets were prepared using the liquid-phase exfoliation method. Strontium ions (Sr 2+ ) were then loaded onto the BP surface via electrostatic self-assembly technology, forming a composite nanomaterial named Black Phosphorus Strontium (BP-Sr) that exhibits both antibacterial properties and the ability to promote soft tissue growth. Utilizing photothermal therapy (PTT), BP-Sr effectively kills bacteria, reduces inflammatory responses, and promotes soft tissue regeneration. This research provides a novel approach for anti-infection treatment and pro-healing strategies for infected wounds.