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September 22, 2025Clinical & Experimental Immunology

Cytokines dynamics and biological sex differences in SARS-CoV-2 infected people in Cameroon

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Authors

HTHillary TeneUniversité de Yaoundé IRNRomuald NgamaleuUniversité de Yaoundé IRDRomeo DjoundaUniversité de Yaoundé I

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Implication

Analysis reveals cytokine variations by sex and suggests implications for immune response and disease severity.

Key Points

  • Males exhibited higher levels of IFNα-2, IL-2, and IL-6 than females upon diagnosis.
  • Cytokine levels trended higher in symptomatic individuals, indicating potential immune response variance.
  • Age-related variations impacted viral load, with individuals aged 40-60 showing significantly higher levels.
  • Cytokine dynamics may influence disease severity and recovery patterns depending on sex and clinical status.

Cite This Study

Tene et al. (2025) studied this question.

synapsesocial.com/papers/68d46fdc31b076d99fa6a5ddhttps://doi.org/10.1093/cei/uxaf063
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