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September 23, 2025PharmaceuticalsOpen Access

The Impact of 24-Month Etanercept Therapy on Changes in Adiponectin, Leptin and Tenascin C Levels in the Blood of Children with Juvenile Idiopathic Arthritis

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Authors

JSJan SiwiecMedical University of Silesia KKKornelia Kuźnik‐TrochaMedical University of Silesia KWKatarzyna Winsz‐SzczotkaMedical University of Silesia

Discussion

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Implication

Observational analysis shows changes in adiponectin, leptin, and tenascin C levels in children with JIA, suggesting TNF-α inhibitors may aid recovery.

Key Points

Etanercept therapy significantly improved adiponectin, leptin, and tenascin C levels in children with JIA.
Children with untreated JIA exhibited altered levels of adiponectin, leptin, and tenascin C compared to healthy peers.
Commercial ELISA tests were utilized to evaluate the dynamics of biomarker changes in blood samples.
The findings support the use of adiponectin, leptin, and tenascin C as potential markers of treatment efficacy in JIA.

Cite This Study

Siwiec et al. (2025) studied this question.

synapsesocial.com/papers/68d4724731b076d99fa6aa8a https://doi.org/10.3390/ph18091423

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Implication

Observational analysis shows changes in adiponectin, leptin, and tenascin C levels in children with JIA, suggesting TNF-α inhibitors may aid recovery.

The Impact of 24-Month Etanercept Therapy on Changes in Adiponectin, Leptin and Tenascin C Levels in the Blood of Children with Juvenile Idiopathic Arthritis

Discussion

Member takes

Implication

Key Points

Cite This Study

The Impact of 24-Month Etanercept Therapy on Changes in Adiponectin, Leptin and Tenascin C Levels in the Blood of Children with Juvenile Idiopathic Arthritis

Discussion

Member takes

Implication

Key Points

Cite This Study

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