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September 23, 2025Frontiers in Cellular and Infection MicrobiologyOpen Access

Progress of single-cell sequencing technology in immunotherapy for tuberculosis

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Authors

XFXinxin FanMCMuxing ChenDWDi Wu

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Overview

Review highlights the role of single-cell sequencing in tuberculosis, revealing challenges and immune mechanisms.

Key Points

  • Single-cell sequencing technology offers critical insights into immune cell behaviors in tuberculosis, enhancing understanding.
  • M72/AS01E vaccine shows 54% efficacy, while challenges in drug-resistant tuberculosis highlight urgent treatment needs.
  • Recent advancements in tuberculosis immunotherapy, including nano-based therapies, demonstrate improved treatment outcomes.
  • Understanding immune mechanisms through single-cell sequencing may lead to new diagnostic markers for tuberculosis.

Cite This Study

Fan et al. (2025) studied this question.

synapsesocial.com/papers/68d4725d31b076d99fa6b511https://doi.org/10.3389/fcimb.2025.1666630
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Progress of Single-Cell Sequencing Technology in Immunotherapeutic to Tuberculosis2024
  2. 2Towards the elimination of tuberculosis: advances in diagnostics, treatment, and vaccination2026
  3. 3A REVIEW ON TUBERCULOSIS: CURRENT CHALLENGES AND RECENT ADVANCES IN TREATMENT2026
  4. 4Advancing the fight against tuberculosis: integrating innovation and public health in diagnosis, treatment, vaccine development, and implementation science2025 · 16 citations
  5. 5Research overview—2025: integrating scientific progress to accelerate global tuberculosis elimination2026 · 1 citations