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September 23, 2025Therapeutic Advances in Pulmonary and Critical Care MedicineOpen Access

Point-of-Care Ultrasound Evaluation of Diaphragm as a Predictor of Extubation Success in Mechanically Ventilated, Malnourished, End-Stage Liver Disease Pretransplant Candidates—Observational Cohort Study

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Authors

ARAdam Muhammad ReidSBSarathi BhattacharyyaZZZian Zhuang

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Overview

Observational cohort study finds diaphragm thickening correlated with extubation success in malnourished ESLD patients.

Key Points

  • Ultrasound assessment indicates diaphragm evaluation may be an essential predictor of extubation success.
  • Among 70 patients, 82.4% tolerated extubation, and diaphragm thickness showed significant differences between groups.
  • Observation utilized point-of-care ultrasound to assess diahpragmatic function and thickening in ESLD patients on ventilation.
  • Findings suggest clinical implications for using diaphragm function assessment in ventilated ESLD patients with malnutrition.

Cite This Study

Reid et al. (2025) studied this question.

synapsesocial.com/papers/68d4725d31b076d99fa6b58ehttps://doi.org/10.1177/29768675251337833
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Also Consider

Synapse has enriched 2 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1A Prospective Study of Indexes Predicting the Outcome of Trials of Weaning from Mechanical Ventilation1991 · 1,390 citations
  2. 2Both high level pressure support ventilation and controlled mechanical ventilation induce diaphragm dysfunction and atrophy2012 · 212 citations