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September 23, 2025

Multi-functional phytoglycogen-derived hydrogel dressings promote the fast closure of diabetic wound in vitro and in vivo

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Authors

JZJingyi ZhengState Key Laboratory of Food Science and TechnologyBPBo PanThe University of SydneyJGJingya GuoSoochow University

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Overview

In vitro and in vivo analyses show that phytoglycogen hydrogels improve healing rates in diabetic wounds, indicating their multi-functional benefits.

Key Points

  • The hydrogel dressing showed a healing rate improvement of 1.76-fold compared to commercial options.
  • Reactive oxygen species clearance was expedited by the hydrogel, promoting cell proliferation and tissue formation.
  • Cationized and oxidized phytoglycogen-based hydrogel demonstrated superior antibacterial and self-healing properties.
  • The dressing modulated key signaling pathways involved in immune responses and inflammation resolution.

Cite This Study

Zheng et al. (2025) studied this question.

synapsesocial.com/papers/68d4726431b076d99fa6b718https://doi.org/10.21203/rs.3.rs-7222605/v1
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Also Consider

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  1. 1Multi-functional phytoglycogen-derived hydrogel dressings promote the fast closure of diabetic wound in vitro and in vivo2026 · 1 citations
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