Etiological spectrum and diagnostic features of lymphadenopathy in People Living with HIV in French Guiana: A 17-years multicenter retrospective case series

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Retrospective analysis identifies opportunistic infections as key causes of lymphadenopathy in PLHIV, highlighting diagnostic challenges.

Opportunistic infections account for 53% of lymphadenopathy causes in PLHIV, emphasizing their prevalence.
Histoplasmosis led as the primary cause (25%), closely followed by tuberculosis (24%) and HIV-reactive lymphadenitis (21%).
The study involved a retrospective case series of 152 PLHIV who underwent lymph node analysis between 2005 and 2021.
These findings support the importance of CD4 count and lymph node size in prompt diagnostic evaluations for PLHIV.

Bourne-Watrin et al. (2025) studied this question.

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