This method demonstrates a novel copper-catalyzed approach to azidation in cyclic compounds, enabling triazole formation.
A photoinduced copper‐catalyzed radical ring‐opening azidation of cyclic oxime esters has been developed for the synthesis of valuable γ ‐azido alkylnitriles. Furthermore, a one‐pot sequential strategy integrating this ring‐opening azidation with copper‐catalyzed azide–alkyne cycloaddition is successfully implemented, enabling the direct construction of 1,2,3‐triazole derivatives in a single operation.
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Yang et al. (2025) studied this question.
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