Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
September 23, 2025ChemPlusChem

The Effect of the Substituent's Nature on the Crystallographic and Quantum‐Chemical Profile of the Fluorine–Fluorine Interaction

View Full Paper
Ask AI
Bookmark
Share

Authors

MPMarija Petković-BenazzouzSJStefan T. JelićMMMiloš Milčić

Discussion

Loading...

Member takes

Overview

Statistical analysis reveals how substituent nature alters F···F interactions and their suitability in supramolecular systems.

Key Points

  • F···F interactions show specific characteristics like antiparallel orientation and long distances, indicating weak noncovalent bonding.
  • Energy profiles indicate that F···F interactions have shallow minima, with optimal distances being between 3.0 to 3.5 Å.
  • The influence of substituent geometry is more profound on F···F interaction strength when bound to aromatic rings compared to alkyl groups.
  • The analysis employed data from the Cambridge Structural Database and quantum-mechanical calculations to assess the interactions.

Cite This Study

Petković-Benazzouz et al. (2025) studied this question.

synapsesocial.com/papers/68d473a631b076d99fa6bfeehttps://doi.org/10.1002/cplu.202500368
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Structural adaptability of aromatic F⋯O contacts: insights from crystal geometry, charge effects and energy decomposition2026
  2. 2Negative σ-Holes on Fluorine in Molecules Revisited: Halogen Bonding or Counterintuitive, Anti-Electrostatic Interactions?2026 · 1 citations
  3. 3Understanding organofluorine chemistry. An introduction to the C–F bond2007 · 4,053 citations
  4. 4Studying the Hemibond: High-Level <i>Ab Initio</i> Calculations on Complexes of Atomic Fluorine with Halogenated Organic Molecules2025
  5. 5The influence of C-F⋯H-X hydrogen-bonding interactions on the reactivity and selectivity of organic reactions.2025