September 23, 2025Journal of Tropical MedicineOpen Access

Epidemiology of Hepatitis B Virus Infection in Nigeria: A Narrative Review of Prevalence, Transmission, Genotypes, Coinfections, and Mortality

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Nigeria has the highest burden of hepatitis B virus infection in sub-Saharan Africa, showing significant variation across populations.
Recent data indicated HBV prevalence rates between 5.4% and 13.6% in the general population, corresponding to about 14.4 million people living with HBV.
Key populations show varied prevalence rates, with blood donors and pregnant women exhibiting rates of up to 14% and 14.1%, respectively.
Approximately 46,000 deaths in 2022 were attributed to hepatitis B, reflecting a concerning mortality rate of 21 per 100,000 population.

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This narrative review summarizes prevalence, transmission modes, and mortality rates of hepatitis B virus in Nigeria, highlighting key research gaps.

Olakunde et al. (2025) studied this question.

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This narrative review summarizes prevalence, transmission modes, and mortality rates of hepatitis B virus in Nigeria, highlighting key research gaps.