Case report reveals linezolid-induced lactic acidosis can trigger automated sepsis alerts, indicating the need for context in diagnosis.
Elevated lactate alone may trigger false sepsis alerts. In this case, linezolid‐induced lactic acidosis mimicked sepsis, triggering automated alerts. Clinicians should consider medication‐related causes of lactate elevation and apply clinical context in interpreting automated alerts to avoid unnecessary interventions, alert fatigue, and improve diagnostic accuracy in sepsis management.
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Kagzi et al. (2025) studied this question.
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