Multicentre study reveals incidence and predictors of lactic acidosis in critically ill patients, indicating need for careful monitoring.
Linezolid-associated lactic acidosis is a frequent and often severe complication in ICU patients, typically developing early during therapy. Sepsis, non-pneumonia infections and norepinephrine use were identified as key risk factors. These findings highlight the need for early recognition and vigilant monitoring of high-risk patients to promote safer use of linezolid in critically ill populations.
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Naseralallah et al. (2026) studied this question.
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