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September 23, 2025Frontiers in EndocrinologyOpen Access

Targeting microRNAs in diabetic retinopathy: from pathogenic mechanisms to therapeutic potentials

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Authors

JCJiajun ChenQingdao UniversityJZJingjing ZhangCapital Medical UniversityCLChanglei LiQingdao University

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Overview

Review highlights the role of microRNAs in diabetic retinopathy pathogenesis, suggesting promising therapeutic targets and biomarkers.

Key Points

  • MicroRNAs are critical regulators influencing the pathogenesis of diabetic retinopathy through multi-target modulation.
  • Specific miRNAs exhibit stage-specific expression patterns, offering potential as non-invasive biomarkers for diabetic retinopathy.
  • The review emphasizes the need for innovative strategies beyond anti-VEGF agents for effective early intervention in diabetic retinopathy.
  • MicroRNA-based therapies using advanced profiling techniques may revolutionize approaches to prevent diabetic retinopathy progression.

Cite This Study

Chen et al. (2025) studied this question.

synapsesocial.com/papers/68d473bb31b076d99fa6ca91https://doi.org/10.3389/fendo.2025.1664604
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