Observational analysis shows the link between statin use and muscle symptoms in older adults, suggesting adverse effects contribute to discontinuation.
Introduction Statins are strongly recommended to reduce major adverse cardiovascular events, making them widely prescribed by health-care providers. Despite this, statins are underutilized in older adults (≥65 years of age), partially related to the fear of adverse effects. Statin associated muscle symptoms (SAMS) are commonly cited as a reason for statin discontinuation.
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Pogge et al. (2025) studied this question.
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